Anti-G is expected to react with red blood cells of which phenotypes?

Prepare for the AAB Medical Technologist (MT) Generalist Exam with flashcards and multiple choice questions. Each question includes hints and explanations to boost your understanding. Get exam-ready now!

The reactivity of Anti-G is primarily associated with the presence of the G antigen, which is found on red blood cells that carry specific combinations of the D antigen and the C/c antigens. The Anti-G antibody reacts with red blood cells that express both D and G antigens due to their genetic linkage.

In the case of the listed phenotypes, the phenotype A+B-C+D-E- contains the D antigen (which is linked to G). Therefore, red blood cells with this phenotype will express the G antigen and are expected to react positively to Anti-G. This explains why Anti-G would specifically interact with red blood cells of this particular phenotype.

Other phenotypes in the choices do not express the G antigen due to their lack of the D antigen or a combination that does not lead to the expression of G, resulting in no reaction with Anti-G. Thus, the option that includes both the D antigen and conditions that promote the G antigen's presence is the one that corresponds to the expected reaction with Anti-G.

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