Which symptom is NOT typically associated with a febrile transfusion reaction?

A febrile transfusion reaction is characterized by an increase in body temperature, which typically occurs along with other symptoms like chills and nausea. Fever is the primary symptom, often accompanied by chills as the body's response to the transfusion. Nausea can also arise during such reactions as part of the overall body's reaction.

In contrast, shortness of breath is not a typical symptom associated with a febrile transfusion reaction. Instead, it may indicate other types of transfusion reactions, such as allergic reactions or transfusion-related acute lung injury (TRALI), which involve respiratory distress. Therefore, recognizing that shortness of breath does not align with the classic symptoms of a febrile transfusion reaction clarifies why it is the correct answer in this context.