AAB Medical Technologist (MT) – Generalist Practice Exam

Question: 1 / 410

Which cell type can differentiate into macrophages in tissue?

Neutrophils

Monocytes

Monocytes are the correct answer because they are a type of white blood cell that circulates in the bloodstream and can migrate into various tissues throughout the body. Once in the tissue, monocytes can differentiate into macrophages, which are essential for immune response and innate defenses. Macrophages play a critical role in phagocytosis, where they engulf and digest cellular debris, pathogens, and other foreign substances.

Neutrophils primarily act as first responders to sites of infection and are designed for rapid response, but they do not differentiate into macrophages. Instead, they perform their functions independently. B lymphocytes and T lymphocytes are both involved in adaptive immunity, with B cells primarily focusing on antibody production and T cells on cellular immunity. Neither directly differentiate into macrophages. Thus, the ability of monocytes to transition into macrophages in tissues highlights their pivotal role in both innate and adaptive immunity.

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B lymphocytes

T lymphocytes

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