A blood donor has the following Rh antisera results: anti-D 0, anti-C +, anti-E 0, anti-c +, anti-e +. What is the donor's Rh genotype?

Prepare for the AAB Medical Technologist (MT) Generalist Exam with flashcards and multiple choice questions. Each question includes hints and explanations to boost your understanding. Get exam-ready now!

To determine the Rh genotype based on the provided antisera results, it's essential to interpret how the presence or absence of specific antibodies correlates with Rh antigens.

In the results given, the donor shows positive reactions with anti-C, anti-c, and anti-e, while being negative for anti-D and anti-E. This outcome suggests the following about the Rh antigens present on the donor's red blood cells:

  1. Anti-D 0 indicates that the donor does not have the D antigen, which means they are Rh-negative.

  2. Anti-C + indicates the presence of the C antigen.

  3. Anti-E 0 indicates the absence of the E antigen.

  4. Anti-c + indicates the presence of the c antigen.

  5. Anti-e + indicates the presence of the e antigen.

Combining these observations leads us to conclude that the donor must possess the following Rh genes:

  • Since D is absent, the genotype must have a lower-case d in both alleles.

  • The positive reactions with anti-C, anti-c, and anti-e demonstrate that the allele must be capable of expressing these minor antigens.

Taking into account these factors, the genotype that fits this analysis

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