A patient has a prothrombin time (PT) of 12 seconds and an activated partial thromboplastin time (aPTT) of 25 seconds. What condition does this indicate?

A prothrombin time (PT) of 12 seconds and an activated partial thromboplastin time (aPTT) of 25 seconds generally indicate normal coagulation function in the context of hemostasis. In a healthy individual, PT values typically range from about 11 to 13.5 seconds, while normal aPTT values range from 30 to 40 seconds, although these can vary slightly depending on the laboratory and methodology used.

The PT specifically assesses the extrinsic pathway of coagulation, whereas aPTT evaluates the intrinsic pathway. Both results falling within their respective normal ranges suggests that the patient does not exhibit significant clotting abnormalities and is likely in normal health.

Conditions such as hemophilia typically present with prolonged aPTT while PT remains normal, liver disease can lead to abnormal PT results due to impaired production of clotting factors, and vitamin K deficiency generally prolongs both PT and aPTT. However, the values given in this scenario do not indicate such disorders and affirm the absence of significant coagulation issues.