A patient with an Rh genotype of DCe/DCe is transfused with Dce/Dce blood. What alloantibody will the patient likely produce?

In this scenario, the patient has the Rh genotype DCe/DCe, meaning they have the D, c, and e antigens present on their red blood cells. They are transfused with Dce/Dce blood, which includes the same D antigen and an e antigen but introduces the c antigen that the patient does not have.

When a patient is exposed to foreign antigens through transfusion, their immune system may recognize the antigens that are not present on their own cells as foreign. In this case, the patient does not have the c antigen, so the introduction of the c antigen from the donor blood can stimulate the patient's immune system to produce antibodies against it. This means the patient is likely to develop anti-c alloantibody in response to the transfusion.

Understanding the principles of Rh typing and the corresponding antibody formation in response to transfusions helps clarify this situation. The specific focus here is on the difference in antigen presence and how that elicits an immune response, particularly with respect to alloantibodies.