What condition automatically disqualifies stored blood from transfusion?

The condition that automatically disqualifies stored blood from transfusion is the presence of clots. Clots in blood can cause severe complications during a transfusion, including the risk of anaphylaxis and embolism, as they may obstruct blood vessels when infused. This makes it crucial to ensure that any blood product is free from clots before transfusion.

While there are concerns regarding temperature and the storage duration of blood, the presence of clots is a more immediate and serious issue that directly impacts patient safety. Blood storage guidelines typically specify that blood should be maintained between certain temperature ranges (usually 1-6°C for red blood cells) and within a specific time frame (up to 42 days depending on the additive solution used). However, blood that has developed clots is considered unsafe regardless of its age or temperature.