What is the most probable Rh genotype of a blood donor tested with positive results for anti-D, anti-C, anti-E, anti-c, and anti-e?

Prepare for the AAB Medical Technologist (MT) Generalist Exam with flashcards and multiple choice questions. Each question includes hints and explanations to boost your understanding. Get exam-ready now!

To determine the most probable Rh genotype of a blood donor based on the positive results for anti-D, anti-C, anti-E, anti-c, and anti-e, it's essential to analyze the results in the context of Rh blood group genetics.

The presence of anti-D indicates that the individual likely has the D antigen, making them Rh positive. However, positive reactions to anti-C, anti-E, anti-c, and anti-e suggest that there are multiple Rh antigens present on the red blood cells. Specifically, the positive reaction to anti-C implies that the C antigen is also present, while the reactions to anti-E, anti-c, and anti-e indicate the presence of respective antigens.

The genotype of interest needs to encompass these alleles.

In the chosen answer of DCe/DcE, the homozygous and heterozygous combinations of the D, C, and e antigens provide a possible configuration. The presence of both D alleles ensures that anti-D is not produced, corroborating the positive D test. Moreover, both the D and C antigens are represented here, satisfying the positive results for anti-C while maintaining a comprehensive system of antigens (D, C, e).

This combination aligns with the need

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