What type of cells are hybridoma cells the fusion of?

Prepare for the AAB Medical Technologist (MT) Generalist Exam with flashcards and multiple choice questions. Each question includes hints and explanations to boost your understanding. Get exam-ready now!

Hybridoma cells are the result of the fusion between B cells and myeloma cells. This process is a key technique in the production of monoclonal antibodies. B cells are responsible for producing specific antibodies against antigens, while myeloma cells are cancerous B cells that divide indefinitely. When these two cell types are fused, the resulting hybridoma possesses the ability to produce a single type of antibody (specificity of the B cell) and has the immortal growth properties of the myeloma cell. This allows for the continuous production of monoclonal antibodies for research, diagnostic, and therapeutic applications.

The other options do not accurately describe the composition of hybridoma cells, as T cells, macrophages, or neutrophils are not involved in the fusion process that leads to hybridoma creation. The fusion specifically relates to B cells and myeloma cells, making that combination essential for the development and functionality of hybridoma cells.

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