Which cells, along with dendritic cells and macrophages, present antigens to T-helper cells?

Prepare for the AAB Medical Technologist (MT) Generalist Exam with flashcards and multiple choice questions. Each question includes hints and explanations to boost your understanding. Get exam-ready now!

B cells, along with dendritic cells and macrophages, play a crucial role in the immune system by presenting antigens to T-helper cells. This process is fundamental for the activation of the adaptive immune response. B cells can capture specific antigens through their B-cell receptors (BCRs), process these antigens, and then present them on their surface bound to major histocompatibility complex (MHC) class II molecules. When T-helper cells recognize these presented antigens, they become activated, leading to a variety of immune responses, including the production of antibodies.

Dendritic cells and macrophages also serve as professional antigen-presenting cells (APCs), but the inclusion of B cells highlights their significant role in linking innate and adaptive immunity. Other types of cells, like neutrophils, T cells, and basophils, have different functions in the immune system and do not primarily serve as antigen-presenting cells to T-helper cells. Neutrophils are mainly involved in the innate response and act as phagocytes, while T cells are effector cells that respond to antigens but do not present them. Basophils play a role in inflammatory responses and allergic reactions but are not directly involved in antigen presentation.

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