Which polysaccharide component does the Cryptococcus antigen latex agglutination test detect in the capsule of Cryptococcus neoformans?

Prepare for the AAB Medical Technologist (MT) Generalist Exam with flashcards and multiple choice questions. Each question includes hints and explanations to boost your understanding. Get exam-ready now!

The Cryptococcus antigen latex agglutination test specifically detects glucuronoxylomannan, which is a key polysaccharide component of the capsule surrounding Cryptococcus neoformans. This polysaccharide plays a crucial role in the pathogenesis of the organism, contributing to its virulence and ability to evade the immune system. The presence of glucuronoxylomannan in the serum or other body fluids correlates with active infection, making it a useful target for diagnosis.

The test utilizes latex beads coated with antibodies that bind to glucuronoxylomannan, causing visible agglutination when the antigen is present. This functionality underscores the importance of glucuronoxylomannan in both the diagnostic process and understanding the organism's biology in a clinical setting. The other components, while related to various biological functions and pathogens, do not play a direct role in the specific detection of Cryptococcus neoformans within the context of this test.

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